منابع مشابه
Red blood cells have a killer touch
JCB • VOLUME 179 • NUMBER 2 • 2007 172 G ene silencing is the sine qua non of differentiation, and reversal of gene silencing paves the way for a cell to adopt a new fate. In a new study, Francesca De Santa, Giaocchino Natoli, and colleagues (European Institute of Oncology, Milan, Italy) identify a desilencing protein that might let cells fi nd new fates during infl ammation. “Under conditions ...
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The cytotoxic activity of natural killer cells is usually tested by radioactive assay CSI Cr release assay), which detects the release of cytoplasmic contents after plasma membrane disintegration of dying cells. In contrast to this indirect evaluation of cytotoxicity, the assessment of cell damage by flow cytometry aims to provide a more exact characterization of the death pathway via detec...
متن کاملHuman natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.
Immunodeficient mouse-human chimeras provide a powerful approach to study host-specific pathogens, such as Plasmodium falciparum that causes human malaria. Supplementation of immunodeficient mice with human RBCs supports infection by human Plasmodium parasites, but these mice lack the human immune system. By combining human RBC supplementation and humanized mice that are optimized for human imm...
متن کاملOptimizing Red Blood Cells Consumption Using Markov Decision Process
In healthcare systems, one of the important actions is related to perishable products such as red blood cells (RBCs) units that its consumption management in different periods can contribute greatly to the optimality of the system. In this paper, main goal is to enhance the ability of medical community to organize the RBCs units’ consumption in way to deliver the unit order timely with a focus ...
متن کاملDog Red Blood Cells
Red blood cells from mature dogs contain less Na and more K than would be the case if they were in Donnan equilibrium with plasma. They have no ouabain-sensitive Na pump, and their membranes are deficient in Na, K-ATPase. Experiments are reported in which dog red cells were first loaded with supranormal quantities of Na and water and then reinjected into the dog. Over the course of 26-40 h the ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2007
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.1792rr4